Clinical Studies of Pueraria Mirifica
The information provided here was acquired from: Medical Plant Research Institute, Department of Medical Sciences, Ministry of Public Health, Thailand.
Pueraria Mirifica is the herb that can be found almost everywhere in Thailand. However, the batches collected in forests located in the North, the West and the North East of Thailand are known to have larger concentration of active microelements due to specific climate conditions. The parts that we use for manufacturing our breast enhancement product are the interconnected tuberous roots, which look like chains of round-shaped bulbs.
There are nine species of Pueraria genus found in Thailand. However, the only one to possess such exceptional effect is Pueraria Mirifica, which can easily be distinguished from other Pueraria species by distinct peculiarities of the flower stamen and its hairy pod.
The tuber enable to There are at least 13 natural health-giving chemicals found in the tuberous roots of Pueraria Mirifica. These chemicals are widely known as “phytoestrogens” comprising the following ones: miroestrol, daidzein, genistin, genistein, B-sitosterol, stigmasterol, coumestrol, pueraria, compesterol, mirificoumestan, kwakhurin and mirificin. Thai people has always believed Peraria Mirifica to possess exceptional rejuvenating characteristics - and used it is a health-giving supplement to their dishes.
Some phytoestrogens found in Pueraria Mirifica are classified as isoflavones (daidzin, daidzein, genistin, genistein and puerarin). The list of elements that belong to other chemical classes includes the following ones: miroestrol and its derivatives, beta-sitosterol, stigmasterol, coumestrol, puerarin, mirificoumestan, kwakhurin, mirificin, b-sitosterol, alkane alcohol, fat, and sugar.
Chemical analysis of Pueraria Mirifica extract has detected a rare estrogenic substance, which was later named “miroestrol”. The amount of miroestrol in Pueraria Mirifica extract equals to 0.002-0.003% and the effect of this substance is estimated to be about twice as powerful as that of female estrogen.
The study of the effect produced by the chemicals found in Pueraria Mirifica on breast cells has been carried out by Emory University School of Medicine in Atlanta, Georgia, USA, and the Department of Obstetrics and Gynecology, Phramongkutklao College of Medicine, Bangkok, Thailand. These studies proved that the extract of Pueraria Mirifica significantly decreases the probability of breast cancer in women. Pueraria mirifica promotes fibroblasts in normal breast cells and inhibits estrogen-dependent breast cancer cells. During the study carried out at the School of Medicine, Saint Mariane University, Tokyo, Japan by Kuramoshi, T. and Smitasiri, Y., 50 healthy menstruating volunteer females, aging 20 to 49, were taking between 100 to 600 mg of Pueraria mirifica root extract a day orally for 7 days, two weeks after menstruation. No reports of abnormally heavy, severe, or missed menstruation were recorded during or short after the test.
The results of Animal Testing: During the years 1960-61 a group of British researchers carried out a test concerning the effect of miroestrol on female rats. The results went beyond all expectations - it was proved that the synthetic estrogen or the animal estrogen or even the human estrogen could easily be substituted by this chemical without any malicious side effects.
The results of Human Testing: The effect of PM root has also been tested on humans in 1961. The research has proved that PM extract has a powerful estrogenic effect on humans. However, that wasn't the first PM-connected human test carried out in the course of history. In 1941, one Thai doctor was using the crude extract of PM roots on his patients. Needless to say that he also recorded certain positive effects.